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Received : 11-06-2021

Accepted : 19-06-2021

Available online : 11-08-2021

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Synergistic effects of Vitamin D and magnesium in non-specific low back ache (nLBA) – A prospective comparative study

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Original Article

Author Details : T P Saravanakumar, Prajwal GS, Ashwin Gobbur*

Volume : 7, Issue : 1, Year : 2021

Article Page : 29-33

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Introduction: Low back ache constitute a group of symptoms with no clear etiopathogenesis and pose a major difficulty for a health care professional to diagnose and treat the disease per se. Low back ache has become permanent disability for certain individuals and interferes with normal functioning of day-to-day life activities.
Objective: This study was undertaken to establish the correlation and functional outcome between combination of Vitamin D & magnesium supplementation and Vitamin D supplementation for patients with non-specific low back ache.
Materials and Methods: An observational comparative study was performed with 117 patients of nonspecific low back ache from June 2019 to May 2020. Out of 117 patients, a total of 60 patients (Group A) were treated with a combination of Vitamin D supplementation along with magnesium tablets for 3 consecutive months and remaining 57 patients (Group B) were treated with Vitamin D supplementation for 3 consecutive months. Both the groups were followed up for 6 months for pain relief assessed by
VAS score and functional improvement in quality of life assessed by Oswestry Low Back Pain Disability Questionnaire.
Results: A significant difference was noted in the Group A compared to Group B which demonstrates an additive effect on the combination used in them. When analysing the change in parameters compared to the pre-interventions state both the groups showed significant improvements. However, upon analysis of the correlation between the parameters with regard to the change among the groups, we noted that Group A showed significant correlation with respect to the Calcium and Vit-D level improvement out of the intervention upon the observed results.
Conclusion: Treatment of non-specific low back ache with vitamin-D and magnesium shows synergistic effects with significant improvement in the functional outcomes and the pre-intervention metabolic parameters.

Keywords: Vitamin D, Magnesium, Low back ache, Spine, Conservative management.

How to cite : Saravanakumar T P , Prajwal Gs, Gobbur A , Synergistic effects of Vitamin D and magnesium in non-specific low back ache (nLBA) – A prospective comparative study. IP Int J Orthop Rheumatol 2021;7(1):29-33

Copyright © 2021 by author(s) and IP Int J Orthop Rheumatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

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